Drugs

Sarcopenia: What a Waste

Sarcopenia, a muscle wasting disease, could shorten your life and is alarmingly prevalent. Why are so many people unaware it exists?

By Robin Donovan

Is Low-Dose Lithium a Better Solution for Major Depression?

Some studies show it’s better than SSRIs—but there’s no incentive to invest in clinical trials.

By David Levine

Repurpose This Drug

How drugs that hit targets for depression and kidney disease could help people suffering physical pain.

By Caren Chesler

Alex Zhavoronkov: Live Long and Prosper

The maniacally focused founder of Insilico Medicine is going all in on AI to discover new medicines and extend lifespan.

By Matthew Hutson

Does the Peer Review Process Need Blockchain?

A new generation of scientists raised on Reddit and Instagram are exploring crowdsourced models of scientific peer review.

By Richard Sprague

What if We Didn’t Have to Test New Drugs on Animals?

As organ-on-a-chip technology comes of age, the bipartisan FDA Modernization Act 2.0 would remove the requirement that new drugs must undergo animal testing before human clinical trials.

By Emily Sohn

Reproducibility in Clinical Trials is Like Trying to Catch a Rabbit by the Tail

Scientists are not routinely sloppy, clinicians don’t usually cheat, and clinical research is generally well designed. So why is it so hard to reproduce results?

By David Warmflash

Perspective: The Human Immunome Project is the Next Big Leap

An insider’s view of the effort to decode and model the entire immune system.

By Jane Metcalfe

New Tech for Gene Therapy Could Advance Longevity

Maybe the science is finally catching up with BioViva CEO Elizabeth Parrish.

By David Warmflash

Perspective: Should I Get the New COVID-19 Bivalent Booster?

Our writer unpacks the data behind the new vaccines and wonders what happened to nuance in the CDC’s recommendations.

By David Warmflash